Category Archives: 生物信息

介绍生物信息学相关知识及其软件的使用

12月 09

TED基因组学与人类未来——中国肿么了？

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【位于视频中大约20:20的位置】印度和中国对世界经济的贡献曾达到40%，不过只是在工业革命期间，现在只占到4.8%。两国合起来有20亿人口，占世界人口的1/3，产生的财富仅占世界的5%。因为他们没有顺势而变，因为统治者把他们的国民看做是农奴，而不是具有共同利益的投资人。统治者不懂得留住受过教育的人才，不刺激商业发展，不做上市，但硅谷懂得这么做，这是为什么硅谷因为懂得网罗人才而取得不断的发展，而不是像印度或中国那样单单去发展集成电路。……【阅读全文】

2月 26

[荐]box plots与BoxPlotR

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box plots

BoxPlotR

This application allows users to generate customized box plots in a number of variants based on their data. A data matrix can be uploaded as a file or pasted into the application. Basic box plots are generated based on the data and can be modified to include additional information. Additional features become available when checking that option. Information about sample sizes can be represented by the width of each box where the widths are proportional to the square roots of the number of observations n. Notches can be added to the boxes. These are defined as +/-1.58*IQR/sqrt(n) which gives roughly 95% confidence that two medians are different. It is also possible to define the whiskers based on the ideas of Spear and Tukey. Additional options of data visualization (violin and bean plots) reveal more information about the underlying data distribution. Plots can be labeled, customized (colors, dimensions, orientation) and exported as eps, pdf and svg files.……【阅读全文】

2月 26

[转]RNA测序研究现状与发展

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参考文献

RNA-seq is a recent and immensely popular technology for cataloging and comparing gene expression. Two papers from the international RGASP consortium report on large-scale competitions to identify the best algorithms for RNA-seq analysis, with surprising variability in the results.……【阅读全文】