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[转]RNA测序研究现状与发展

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RNA-seq is a recent and immensely popular technology for cataloging and comparing gene expression. Two papers from the international RGASP consortium report on large-scale competitions to identify the best algorithms for RNA-seq analysis, with surprising variability in the results.……【阅读全文】

十二 07

[荐]Intermediate R/Bioconductor for High-Throughput Sequence Analysis

Intermediate R/Bioconductor for High-Throughput Sequence Analysis introduces users with some R experience to common Bioconductor work flows for sequence analysis. The course involves a combination of presentations and hands-on exercises. Our starting point is BAM files created by aligning short reads to a reference genome. Topics include exploratory analysis (GenomicRanges, Rsamtools); assessing differential expression of known genes (DESeq); detection, calling, and manipulation of variants (VariantTools, VariantAnnotation). We learn how to integrate results with curated gene and genomic annotations (GenomicFeatures), and to visualize results (GViz, ggbio).……【阅读全文】

12

[转]《科学》:明年六大科学领域值得关注

原文链接:《科学》:明年六大科学领域值得关注

12月21日出版的美国《科学》杂志认为,2013年有6大科学领域值得关注:单细胞测序、“普朗克”探测微波背景辐射、人类连接组计划、探索南极冰下世界、癌症免疫疗法和基础植物研究。……【阅读全文】

12

[转]《时代》杂志评出2012年十大医学突破

原文链接:《时代》杂志评出2012年十大医学突破

美国《时代》杂志评选的各领域年度“十大”排名已于近日陆续出炉,医学领域“十大”突破也深入人心。涵盖了生命基础研究、艾滋病与癌症治疗突破、干细胞与再生医学、青少年健康等多方面公众关心的热点。……【阅读全文】