产生深度测序模拟数据的程序

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  1. DNAA中的dwgsim

    2. DNAA is the DNA analysis package, for analyzing next-generation post-alignment whole genome resequencing data. Specifically, DNAA is able to find structural variation, SNP and indel variants, as well as evaluating the mapping and data quality.
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  2. Grinder

    3. Grinder is a open-source bioinformatic tool to create artificial shotgun and amplicon sequence libraries with specific error profiles: simulated sequencing projects (like FlowSim), metagenomes (like MetaSim) or pyrotag datasets (16S rDNA).
    备注：除了可以直接在命令行中使用Grinder外，也可以通过API在Perl脚本中调用它！
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如果你知道其他类似的程序，欢迎补充！